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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPN1
All Species:
36.67
Human Site:
S518
Identified Species:
67.22
UniProt:
P04843
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P04843
NP_002941.1
607
68569
S518
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Chimpanzee
Pan troglodytes
XP_001139195
607
68657
S518
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Rhesus Macaque
Macaca mulatta
XP_001097494
607
68713
S518
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Dog
Lupus familis
XP_848830
607
68558
S518
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YQ5
608
68510
S519
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Rat
Rattus norvegicus
P07153
605
68286
S516
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518675
326
37335
E241
G
K
K
T
L
E
T
E
H
K
A
L
T
N
E
Chicken
Gallus gallus
XP_414360
596
67229
S507
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Frog
Xenopus laevis
NP_001082504
595
67243
T506
T
L
N
S
G
K
K
T
L
E
T
E
H
K
N
Zebra Danio
Brachydanio rerio
NP_922916
598
67598
T509
A
L
N
S
G
R
K
T
L
E
A
E
H
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995680
458
51691
T373
S
S
D
I
R
L
S
T
P
Y
S
I
S
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782614
603
67267
K514
A
F
R
A
T
L
K
K
I
E
G
E
H
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41543
476
54053
D391
P
E
G
A
E
I
F
D
I
D
S
P
V
P
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.6
96.2
N.A.
95
94.4
N.A.
48.2
83.8
77.7
70.8
N.A.
34.9
N.A.
N.A.
52.8
Protein Similarity:
100
99.6
99
98
N.A.
98.3
98
N.A.
51.7
91
88.9
85.3
N.A.
50.9
N.A.
N.A.
71.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
86.6
60
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
93.3
80
N.A.
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
0
0
0
0
0
0
16
0
0
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
8
0
8
0
77
0
77
0
0
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
8
0
70
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
77
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
16
0
0
8
0
0
0
% I
% Lys:
0
8
8
0
0
62
77
8
0
8
0
0
0
62
0
% K
% Leu:
0
70
0
0
8
16
0
0
70
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
70
0
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
8
0
0
0
0
0
0
0
24
0
% R
% Ser:
8
8
0
70
0
0
8
54
0
0
16
0
8
0
8
% S
% Thr:
62
0
0
8
8
0
8
24
0
0
62
0
8
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _